UFM1 activating enzyme Recombinant Protein
Product Specifications
Background
UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localizes to the nucleus in presence of SUMO2.
NCBI Gene ID
79876
Swiss Prot
Q9GZZ9
Accession Number
Q9GZZ9
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl pH 8.0,1mM DTT, 10% glycerol, 50mM NaCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-228
Calculated Molecular Weight
47 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Ubiquitin like modifier activating enzyme 5
NCBI Organism
Homo sapiens
Other Product Names
Ubiquitin-like modifier-activating enzyme 5, ThiFP1, UFM1-activating enzyme, Ubiquitin-activating enzyme E1 domain-containing protein 1, UBE1DC1, UBA5
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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