TYRO3 Recombinant Protein
Product Specifications
Background
Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.
NCBI Gene ID
7301
Swiss Prot
Q06418
Accession Number
AAH51756
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-759
Calculated Molecular Weight
68.2 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
TYRO3 protein tyrosine kinase
NCBI Organism
Homo sapiens
Background Reference 01
Shimojima M., et al., 2006, J. Virol. 80:10109-10116.
Background Reference 02
Cosemans J.M., et al., 2010, J. Thromb. Haemost. 8:1797-1808.
Background Reference 03
Heiring C., et al., 2004, J. Biol. Chem. 279:6952-6958.
Other Product Names
TYRO3, BYK, DTK, RSE, SKY, TIF
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal Caspase-12 Antibody [PerCP]](https://cdn.genprice.uk/genprice/genprice2.png)
