DR3 / TNFRSF25 Recombinant Protein
Product Specifications
Background
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily. TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling. TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
CAS Number
9000-83-3
NCBI Gene ID
8718
Swiss Prot
Q93038
Accession Number
AAI17190
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Other
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
45.5 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 25
NCBI Organism
Homo sapiens
Background Reference 01
Kitson J., et al., 1996, Nature 384:372-375.
Background Reference 02
Bodmer J.-L., et al., 1997, Immunity 6:79-88.
Background Reference 03
Marsters S.A., et al., 1996, Curr. Biol. 6:1669-1676.
Other Product Names
TNFRSF25, DR3, APO3, DDR3, TNFRSF12, WSL, WSL1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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