DR6 Recombinant Protein
Product Specifications
Background
Tumor necrosis factor receptor superfamily member 21 (TNFRSF21) is also known as death receptor 6 (DR6), which is a member of the TNF-receptor superfamily. TNFRSF21 contains one death domain and four TNFR-Cys repeats. TNFRSF21 / DR6 has been shown to activate NF-κB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors.
CAS Number
9000-83-3
NCBI Gene ID
27242
Swiss Prot
O75509
Accession Number
AAH17730
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis
Purity
>90% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
60.2 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 21
NCBI Organism
Homo sapiens
Background Reference 01
Pan G., et al., 1998, FEBS Lett. 431 (3) : 351–356.
Background Reference 02
Kuester M., et al., 2011, J. Mol. Biol. 409 (2) : 189–201.
Other Product Names
TNFRSF21, DR6, CD358, BM-018
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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