FN14 Recombinant Protein
Product Specifications
Background
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is also known as Fibroblast growth factor-inducible immediate-early response protein 14 (FN14 or FGF-inducible 14), Tweak-receptor, CD antigen CD266. TNFRSF12A contains one TNFR-Cys repeat. TNFRSF12A is highly expressed in heart, placenta and kidney. TNFRSF12A is receptor for TNFSF12/TWEAK, and is weak inducer of apoptosis in some cell types. TNFRSF12A / FN14 promotes angiogenesis and the proliferation of endothelial cells.
NCBI Gene ID
51330
Swiss Prot
Q9NP84
Accession Number
AAH02718
Tag
N-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-735
Calculated Molecular Weight
33 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 12A
NCBI Organism
Homo sapiens
Background Reference 01
Wiley S.R., et al., 2001, Immunity 15:837-846.
Background Reference 02
He F., et al., 2009, Protein Sci. 18:650-656.
Other Product Names
TNFRSF12A, FGF-inducible 14, FN14, TweakR, CD266
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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