TNF-like 1 Recombinant Protein
Product Specifications
Background
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial cells. TNFSF15 is also able to regulate the expression of several important genes involved in angiogenesis. These findings are consistent with the view that TNFSF15 functions as an autocrine cytokine to inhibit angiogenesis and stabilize the vasculature.
NCBI Gene ID
326623
Swiss Prot
Q5UBV8
Accession Number
Q5UBV8
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-684
Calculated Molecular Weight
20 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Tumor necrosis factor (ligand) superfamily, member 15
NCBI Organism
Mus musculus
Other Product Names
Tumor Necrosis Factor Ligand Superfamily Member 15, TNF Ligand-Related Molecule 1, Vascular Endothelial Cell Growth Inhibitor, TNFSF15, TL1, VEGI, TL1A
Species
Mouse
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
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