TNF alpha Recombinant Protein

Product Specifications

Background

Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.

CAS Number

9000-83-3

NCBI Gene ID

21926

Swiss Prot

P06804

Accession Number

P06804

Tag

Tag Free

Type

Recombinant Proteins

Source

E. coli

Field of Research

Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction

Buffer

Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

16.4 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Tumor necrosis factor

NCBI Organism

Mus musculus

Other Product Names

Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor, Membrane Form; Tumor Necrosis Factor, Soluble Form; Tnf; Tnfa; Tnfsf2