Tryptophan synthase beta chain Recombinant Protein
Product Specifications
Background
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as humans. Tryptophan synthase typically exists as an alpha- beta beta - alpha complex.The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate: L-serine + 1-C- (indol-3-yl) glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O.The beta subunits catalyze the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.
NCBI Gene ID
945768
Swiss Prot
P0A879
Accession Number
P0A879
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-623
Calculated Molecular Weight
43.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Tryptophan synthase, beta subunit
NCBI Organism
Escherichia coli str. K-12 substr. MG1655
Other Product Names
Tryptophan synthase beta chain, trpB, Trp B
Species
E. coli
Physical Properties
Lyophilized
CAS Number
9000-83-3
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