Tripeptidyl-Peptidase I Recombinant Protein
Product Specifications
Background
Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2) .
NCBI Gene ID
1200
Swiss Prot
O14773
Accession Number
O14773
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Neuroscience
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,1mM GaCl2,10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-745
Calculated Molecular Weight
60.35 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Tripeptidyl peptidase 1
NCBI Organism
Homo sapiens
Other Product Names
Tripeptidyl-Peptidase 1, TPP-1, Cell Growth-Inhibiting Gene 1 Protein, Lysosomal Pepstatin-Insensitive Protease, LPIC, Tripeptidyl Aminopeptidase, Tripeptidyl-Peptidase I, TPP-I, TPP1, CLN2
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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