Transthyretin Recombinant Protein
Product Specifications
Background
Transthyretin (TTR) is also known as Prealbumin, ATTR, TBPA, PALB, which belongs to the transthyretin family. Transthyretin / TTR is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol-binding protein bound to retinol. In cerebrospinal fluid TTR is the primary carrier of T4. TTR also acts as a carrier of retinol (vitamin A) through its association with retinol-binding protein (RBP) in the blood and the CSF. Less than 1% of TTR's T4 binding sites are occupied in blood. TTR misfolding and aggregation is known to be associated with the amyloid diseases.
CAS Number
9000-83-3
NCBI Gene ID
7276
Swiss Prot
P02766
Accession Number
NP_000362
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Homeostasis, Neuroscience
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
14.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Transthyretin
NCBI Organism
Homo sapiens
Background Reference 01
Getz R.K., et al., 1999, Exp. Eye Res. 68:629-636.
Background Reference 02
Herbert J., et al., 1986, Neurology 36:900-911.
Background Reference 03
Mita S., et al., 1984, Biochem. Biophys. Res. Commun. 124:558-564.
Other Product Names
Transthyretin, TTR, Prealbumin, TBPA, ATTR, PALB, CTS, CTS1, HsT2651
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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