TGF beta 2 Recombinant Protein

Product Specifications

Background

Transforming growth factor beta 2 (TGF- beta 2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF- beta 2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF- beta isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF- beta receptor type II (T beta R-II), and a TGF- beta receptor type I (T beta R-I) . Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF- beta expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

CAS Number

9000-83-3

NCBI Gene ID

21808

Swiss Prot

P27090

Accession Number

P27090

Tag

Tag Free

Type

Recombinant Proteins

Source

Human Cells

Buffer

Lyophilized from a 0.2 um filtered solution of 4 mM HCl. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

12.7 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Transforming growth factor, beta 2

NCBI Organism

Mus musculus

Other Product Names

TGFB2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, MGC116892, Polyergin, TGF-beta2, TGF-beta-2, transforming growth factor beta-2