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Transcriptional Repressor CTCF Recombinant Protein

Product Specifications

Background

Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. In addition, CTCF is also indispensable in the epigenetic regulation and chromatin remodeling.

NCBI Gene ID

10664

Swiss Prot

P49711

Accession Number

P49711

Tag

Tag Free

Type

Recombinant Proteins

Source

E. coli

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=92-077

Calculated Molecular Weight

16.9 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

CCCTC-binding factor

NCBI Organism

Homo sapiens

Other Product Names

Transcriptional Repressor CTCF, 11-Zinc Finger Protein, CCCTC-Binding Factor, CTCFL Paralog, CTCF

Species

Human

Physical Properties

Lyophilized

CAS Number

9000-83-3

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