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TPO Recombinant Protein (Animal Free)

Product Specifications

Background

TPO is a lineage-specific growth factor produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor, and acts as an important regulator of circulating platelets. Human and murine TPO exhibit cross-species reactivity. Recombinant Murine TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

CAS Number

9000-83-3

NCBI Gene ID

21832

Swiss Prot

P40226

Type

Recombinant Proteins

Source

E. coli

Field of Research

Immunology, Stem Cell

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Shipping Conditions

Room Temp

Storage Conditions

The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

NCBI Official Name

Thrombopoietin

NCBI Organism

Mus musculus

Other Product Names

Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF

Species

Human, Mouse

Physical Properties

Lyophilized

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