TNF-R1 Recombinant Protein
Product Specifications
Background
TNF-R1 is a receptor for TNF-alpha and homotrimeric lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
CAS Number
9000-83-3
NCBI Gene ID
7132
Swiss Prot
P25942
Accession Number
P19438
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction, Other
Concentration
1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 50 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 1A
NCBI Organism
Homo sapiens
Other Product Names
P55, CD120a, TNFRSF 1A, Tumor Necrosis Factor Receptor Superfamily Member 1A, TNF Receptor 1
Species
Human, Mouse
Protein ID
4507575
Physical Properties
Lyophilized
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