ST2 Recombinant Protein
Product Specifications
Background
The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
CAS Number
9000-83-3
NCBI Gene ID
9173
Swiss Prot
Q9Y5C1
Accession Number
Q01638
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Innate Immunity
Concentration
~0.5mg/ml
Buffer
0.2um-filtered solution in PBS, pH 7.2.
Shipping Conditions
Blue Ice
Storage Conditions
Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Interleukin 1 receptor like 1
NCBI Organism
Homo sapiens
Other Product Names
Interleukin-1 Receptor-like 1, IL-1 Receptor-like 1, IL1RL1, IL-33 Receptor, Interleukin-33 Receptor
Species
Human
Protein ID
116242527
Physical Properties
Liquid
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