EGF R Recombinant Protein
Product Specifications
Background
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4) . Mutations affecting EGFR expression or activity could result in cancer.
CAS Number
9000-83-3
NCBI Gene ID
613027
Swiss Prot
P55245
Accession Number
P55245
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
95.3 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Epidermal growth factor receptor
NCBI Organism
Macaca mulatta
Background Reference 01
Herbst RS, 2004, Int. J. Radiat. Oncol. Biol. Phys. 59 (2 Suppl) : 21–6.
Background Reference 02
Zhang H, et al.,2007, Journal of Clinical Investigation 117 (8) :2051-2058.
Other Product Names
EGFR, ERBB, ERBB1, HER1, PIG61, mENA
Tested Applications
WB
Species
Rhesus monkey
Physical Properties
Lyophilized
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