BMPR1A Recombinant Protein
Product Specifications
Background
The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290) . The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.
CAS Number
9000-83-3
NCBI Gene ID
657
Swiss Prot
P36894
Accession Number
CAA80257
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Infectious Disease, Obesity, Signal Transduction
Purity
>97% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
15.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Bone morphogenetic protein receptor, type IA
NCBI Organism
Homo sapiens
Background Reference 01
Mishina Y, Starbuck MW , et al.,2004, J. Biol. Chem. 279 (26) : 27560–6.
Background Reference 02
Song L, Fässler R, et al., 2007, Dev Biol. 301 (1) :276-86.
Other Product Names
BMPR-1A, ALK-3, 10q23del, ACVRLK3, CD292, SKR5
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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