Carboxypeptidase E Recombinant Protein
Product Specifications
Background
The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.
NCBI Gene ID
1363
Swiss Prot
P16870
Accession Number
P16870
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Neuroscience, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,1mM ZnCl2,10%Glycerol, pH7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-840
Calculated Molecular Weight
47.1 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Carboxypeptidase E
NCBI Organism
Homo sapiens
Other Product Names
Carboxypeptidase E (CPE for short), Carboxypeptidase H, Enkephalin convertase, Prohormone-processing carboxypeptidase, CPE
Species
Human
Protein ID
530394832
Physical Properties
Liquid
CAS Number
9000-83-3
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