CD3 epsilon Recombinant Protein
Product Specifications
Background
T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
CAS Number
9000-83-3
NCBI Gene ID
12501
Swiss Prot
P22646
Accession Number
P22646
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
36 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
T-cell surface glycoprotein CD3 epsilon chain
NCBI Organism
Mus musculus
Background Reference 01
Gold DP, et al., 1986, Nature 321 (6068) : 431–4.
Background Reference 02
Clevers HC, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (21) : 8156–60.
Background Reference 03
Gil J, et al., 2011, J Clin Invest, 121 (10) :3872-6.
Background Reference 04
Lu X, et al.,2011, Hematology, 16 (3) :185-9.
Other Product Names
FLJ18683, T3E, TCRE, CD3E, CD3-epsilon
Tested Applications
WB
Species
Mouse
Physical Properties
Lyophilized
Frequently Asked Questions
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