CD3 epsilon&CD3 gamma Heterodimer Recombinant Protein

Product Specifications

Background

T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

CAS Number

9000-83-3

NCBI Gene ID

916

Swiss Prot

P07766

Accession Number

NP_000724.1 (CD3E) & AAI13831.1 (CD3G)

Tag

His Tag & Fc Tag & Flag Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Immunology

Purity

>95% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

39.2 kDa (CD3E) & 38.6 kDa (CD3G)

Applications Notes

Human CD3E&CD3G Heterodimer Protein, Fc, His Tag&Fc, Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3G) . Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus, followed by a polyhist