SRBC Recombinant Protein
Product Specifications
Background
T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.
NCBI Gene ID
914
Swiss Prot
P06729
Accession Number
AAH33583
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology, Other
Purity
>98% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-098
Calculated Molecular Weight
22.7 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
CD2 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Wilkins A., et al., 2003, Curr Protein Pept Sci 4 (5) : 367–73.
Background Reference 02
Yang J., et al., 2001, Curr Protein Pept Sci 2 (1) : 1–17.
Background Reference 03
Bodian D.L., et al., 1994, Structure 2:755-766.
Other Product Names
CD2, SRBC, LFA-2, T11
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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