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SRBC Recombinant Protein

Product Specifications

Background

T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.

CAS Number

9000-83-3

NCBI Gene ID

914

Swiss Prot

P06729

Accession Number

AAH33583

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Immunology, Other

Purity

>98% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

22.7 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

CD2 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Wilkins A., et al., 2003, Curr Protein Pept Sci 4 (5) : 367–73.

Background Reference 02

Yang J., et al., 2001, Curr Protein Pept Sci 2 (1) : 1–17.

Background Reference 03

Bodian D.L., et al., 1994, Structure 2:755-766.

Other Product Names

CD2, SRBC, LFA-2, T11

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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