TRIM Recombinant Protein
Product Specifications
Background
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor) /CD3 complex at the surface of T-cells.
NCBI Gene ID
50852
Swiss Prot
Q6PIZ9
Accession Number
Q6PIZ9
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Immunology, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, 10% Glycerol, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-074
Calculated Molecular Weight
19.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
T cell receptor associated transmembrane adaptor 1
NCBI Organism
Homo sapiens
Other Product Names
T-Cell Receptor-Associated Transmembrane Adapter 1, T-Cell Receptor-Interacting Molecule, TRIM, pp29/30, TRAT1, TCRIM, HSPC062
Species
Human
Protein ID
190684679
Physical Properties
Liquid
CAS Number
9000-83-3
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