SOD1 Recombinant Protein
Product Specifications
Background
Superoxide dismutase [Cu-Zn] (SOD1) is also known as superoxide dismutase 1 (hSod1), an enzyme that in humans is encoded by the SOD1 gene, located on chromosome 21. SOD1 can bind copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. The encoded isozyme (SOD1) is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide. Furthermore, the mutations of SOD1 gene can result in a neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord.
NCBI Gene ID
6647
Swiss Prot
P00441
Accession Number
AAH01034
Tag
His Tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-950
Calculated Molecular Weight
16.8 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Superoxide dismutase 1, soluble
NCBI Organism
Homo sapiens
Background Reference 01
Kostrzewa M., et al.,1996, Hum. Genet. 98:48-50.
Background Reference 02
Banci L., et al., 2013, ChemBioChem 14:1839-1844.
Background Reference 03
Rosen D.R., et al., 1993, Nature 362:59-62.
Other Product Names
SOD1, Superoxide dismutase 1, hSod1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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