SOD2 Recombinant Protein
Product Specifications
Background
Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.
NCBI Gene ID
6648
Swiss Prot
P04179
Accession Number
P04179
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Cell Cycle, Neuroscience, Obesity, Signal Transduction, Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-789
Calculated Molecular Weight
23.24 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Superoxide dismutase 2, mitochondrial
NCBI Organism
Homo sapiens
Other Product Names
Superoxide Dismutase [Mn] Mitochondrial, SOD2, Mn-SOD
Species
Human
Protein ID
767957252
Physical Properties
Liquid
CAS Number
9000-83-3
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