Sulfotransferase 1A1 Recombinant Protein

Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver, lung, adrenal, brain, platelets, and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.

Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl,1mM EDTA, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Sulfotransferase 1A1, ST1A1, Aryl sulfotransferase 1, HAST1/HAST2, Phenol Sulfotransferase 1, Phenol-Sulfating Phenol Sulfotransferase 1, P-PST 1, ST1A3, Thermostable Phenol Sulfotransferase, Ts-PST, SULT1A1, STP, STP1, OK/SW-cl.88