SCF Recombinant Protein
Product Specifications
Background
Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.
CAS Number
9000-83-3
NCBI Gene ID
17311
Swiss Prot
O35516
Accession Number
AAH11322
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Immunology, Signal Transduction
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Kit ligand
NCBI Organism
Mus musculus
Other Product Names
Stem Cell Factor, c-Kit Ligand, Kit Ligand, Mast Cell Grow Factor, MGF
Species
Mouse
Protein ID
15030139
Physical Properties
Lyophilized
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