SCF Recombinant Protein
Product Specifications
Background
Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.
NCBI Gene ID
4254
Swiss Prot
Q6XQN6
Accession Number
NP_003985
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Immunology, Signal Transduction, Stem Cell
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 μ l sterile water. Add 1X PBS to the desired protein concentration.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-539
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
KIT ligand
NCBI Organism
Homo sapiens
Other Product Names
Stem Cell Factor, c-Kit Ligand, Kit Ligand, Mast Cell Grow Factor, MGF
Species
Human
Protein ID
4580420
Physical Properties
Lyophilized
CAS Number
9000-83-3
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