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SCF Recombinant Protein

Product Specifications

Background

Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF) and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/cKit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.

NCBI Gene ID

4254

Swiss Prot

P0A5L6

Accession Number

NP_003985

Tag

Fc Tag

Type

Recombinant Proteins

Source

CHO cells

Field of Research

Immunology, Signal Transduction, Stem Cell

Buffer

Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 100 μ l sterile water. Add 1X PBS to the desired protein concentration.

Shipping Conditions

Room Temp

Storage Conditions

Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=90-537

Applications Notes

This recombinant proteins is for research use only.

NCBI Official Name

KIT ligand

NCBI Organism

Homo sapiens

Other Product Names

Stem Cell Factor, c-Kit Ligand, Kit Ligand, Mast Cell Grow Factor, MGF

Species

Human

Protein ID

4580420

Physical Properties

Lyophilized

CAS Number

9000-83-3

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