Spondin 2 Recombinant Protein
Product Specifications
Background
Spondin-2, also referred to as mindin, belongs to the F-spondin family of secreted extracellular matrix proteins. Spondins are characterised by the presence of F-spondin domains 1 and 2 (FS1 and FS2) at the N-terminus and a thrombospondin-type 1 repeat (TSR1) domain at the C-terminus. Spondin-2 functions as a pattern-recognition molecule for bacterial and viral pathogens and as an integrin ligand for inflammatory cell recruitment and T cell priming. In addition to its roles in promoting neuron outgrowth and inhibiting both cancer and angiogenesis, Spondin-2 plays an important role in the initiation of the immune response and is involved in inflammatory processes.
NCBI Gene ID
10417
Swiss Prot
Q9BUD6
Accession Number
Q9BUD6
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-655
Calculated Molecular Weight
34.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Spondin 2
NCBI Organism
Homo sapiens
Other Product Names
Spondin-2, Differentially expressed in cancerous and non-cancerous lung cells 1, DIL-1, Mindin, SPON2
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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