Spondin 2 Recombinant Protein
Product Specifications
Background
Spondin-2, also referred to as mindin, belongs to the F-spondin family of secreted extracellular matrix proteins. Spondins are characterised by the presence of F-spondin domains 1 and 2 (FS1 and FS2) at the N-terminus and a thrombospondin-type 1 repeat (TSR1) domain at the C-terminus. Spondin-2 functions as a pattern-recognition molecule for bacterial and viral pathogens and as an integrin ligand for inflammatory cell recruitment and T cell priming. In addition to its roles in promoting neuron outgrowth and inhibiting both cancer and angiogenesis, Spondin-2 plays an important role in the initiation of the immune response and is involved in inflammatory processes.
CAS Number
9000-83-3
NCBI Gene ID
10417
Swiss Prot
Q9BUD6
Accession Number
Q9BUD6
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
34.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Spondin 2
NCBI Organism
Homo sapiens
Other Product Names
Spondin-2, Differentially expressed in cancerous and non-cancerous lung cells 1, DIL-1, Mindin, SPON2
Species
Human
Physical Properties
Lyophilized
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