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Rhesus macaque SLAMF7 / CRACC / CD319 Recombinant Protein

Product Specifications

Background

SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.

Accession Number

XP_001117618.1

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Purity

>90% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=11-463

Calculated Molecular Weight

24.4 kDa

Applications Notes

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.4 kDa. The protein migrates as 35-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Background Reference 01

Bouchon A., et al., 2001, J. Immunol. 167:5517-5521.

Background Reference 02

Murphy J.J., et al., 2002, Biochem. J. 361:431-436.

Other Product Names

SLAMF7, CD319, CS1, CRACC,19A, FOAP-12

Tested Applications

WB

Species

Rhesus monkey

Physical Properties

Lyophilized

CAS Number

9000-83-3

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