SIGLEC5 Recombinant Protein
Product Specifications
Background
Sialic acid-binding Ig-like lectin 5 (SIGLEC5) is also known as CD33 antigen-like 2 (CD33L2), Obesity-binding protein 2 (OB-BP2), CD antigen CD170, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 / CD170 is expressed by monocytic / myeloid lineage cells. SIGLEC-5 / CD33-L2 binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
CAS Number
9000-83-3
NCBI Gene ID
8778
Swiss Prot
O15389
Accession Number
AAH29896
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
73 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Sialic acid binding Ig-like lectin 5
NCBI Organism
Homo sapiens
Background Reference 01
Cornish A.L., et al., 1998, Blood 92:2123-2132.
Background Reference 02
Patel N., et al., 1999, J. Biol. Chem. 274:22729-22738.
Background Reference 03
Zhuravleva M.A., et al., 2008, J. Mol. Biol. 375:437-447.
Other Product Names
SIGLEC5, OB-BP2, CD170, CD33L2
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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