2',3'-cGAMP
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ) . 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm[1].
Product Specifications
CAS Number
[1441190-66-4]
Product Name Alternative
2'-3'-cyclic GMP-AMP
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Endogenous Metabolite; IFNAR; STING
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-3-cgamp.html
Purity
99.95
Solubility
H2O : ≥ 50 mg/mL
Smiles
OC1([H])[C@](OP(O)(OC[C@](O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@@H]4O)([H])[C@@]4([H])O5)=O)([H])[C@H](N6C(NC(N)=NC7=O)=C7N=C6)O[C@]1([H])COP5(O)=O
Molecular Formula
C20H24N10O13P2
Molecular Weight
674.41
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Available Sizes
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