SERPINA3 Recombinant Protein
Product Specifications
Background
Serpin A3 is also known as Alpha-1-antichymotrypsin (ACT or AACT), Cell growth-inhibiting gene 24/25 protein, which belongs to the serpin family. Serpin A3 can bind DNA. Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
CAS Number
9000-83-3
NCBI Gene ID
12
Swiss Prot
P01011
Accession Number
AAH03559
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cell Cycle, Neuroscience, Obesity, Signal Transduction
Purity
>95% as determined by SDS-PAGE.
Buffer
20 mM HEPES, 150 mM NaCl, pH 7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
46 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
NCBI Organism
Homo sapiens
Background Reference 01
Rubin H., et al., 1990, J. Biol. Chem. 265:1199-1207.
Background Reference 02
Kroczynska B., et al., 2004, J. Biol. Chem. 279:11432-11443.
Background Reference 03
Liu T., et al., 2005, J. Proteome Res. 4:2070-2080.
Other Product Names
SERPINA3, ACT, AACT, GIG24, GIG25
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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