What is the catalog number for SHMT1 Recombinant Protein?

The catalog number for SHMT1 Recombinant Protein is 91-687.

What sizes are available for SHMT1 Recombinant Protein?

SHMT1 Recombinant Protein is available in the following size(s): 0.05 mg.

Is SHMT1 Recombinant Protein in stock?

SHMT1 Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

SHMT1 Recombinant Protein

Product Specifications

Background

Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.

CAS Number

9000-83-3

NCBI Gene ID

6470

Swiss Prot

P34896

Accession Number

P34896

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Obesity, Signal Transduction

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.