Sentrin-specific protease 2 Recombinant Protein
Product Specifications
Background
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
CAS Number
9000-83-3
NCBI Gene ID
59343
Swiss Prot
Q9HC62
Accession Number
Q9HC62
Tag
N-6 His, SUMO tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle
Buffer
Supplied as a 0.2 um filtered solution of 50mM HEPES,5% glycerol pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
39.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
SUMO1/sentrin/SMT3 specific peptidase 2
NCBI Organism
Homo sapiens
Other Product Names
Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2., SENP2
Species
Human
Physical Properties
Liquid
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