Semaphorin 4D Recombinant Protein
Product Specifications
Background
Semaphorin-4D is also known as A8, BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
CAS Number
9000-83-3
NCBI Gene ID
10507
Swiss Prot
Q92854
Accession Number
Q92854
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
106.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Semaphorin 4D
NCBI Organism
Homo sapiens
Other Product Names
Semaphorin-4D is also known as A8, BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain., SEMA4D, CD100
Species
Human
Physical Properties
Lyophilized
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