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Semaphorin 4D Recombinant Protein

Product Specifications

Background

Semaphorin-4D is also known as A8, BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.

NCBI Gene ID

10507

Swiss Prot

Q92854

Accession Number

Q92854

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=91-858

Calculated Molecular Weight

80.2 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Semaphorin 4D

NCBI Organism

Homo sapiens

Other Product Names

Semaphorin-4D is also known as A8, BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain., CD100, SEMA4D

Species

Human

Physical Properties

Lyophilized

CAS Number

9000-83-3

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