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SARS-CoV-2 (COVID-19) Delta Variant Spike S1 (His-Avi Tag) Recombinant Protein

Product Specifications

Background

SARS-CoV-2 delta variant, a variant of concern (VOC), known as B.1.617.2, was detected in India in October of 2020. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 99% of the cases. This variant carries at least 13 mutations in spike protein across the sub lineages, including L452R, D614G, P681R and K417N, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Delta variant was observed globally, which is at least 2.5 times more contagious as the other variants. The Delta variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent.

CAS Number

9000-83-3

NCBI Gene ID

43740578

Swiss Prot

P0DTC1

Accession Number

QHD43416.1

Tag

His-Avi tag at C-terminus

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Infectious Disease, COVID-19

Purity

> 90% as determined by Bis-Tris PAGE

Buffer

PBS (pH 7.4) .

Shipping Conditions

Dry Ice

Storage Conditions

Store in working aliquots at -70˚ C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Calculated Molecular Weight

120 kD

Applications Notes

This recombinant protein can be used for WB and ELISA. For research use only.

NCBI Official Name

Surface glycoprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Background Reference 01

Zhang et al. JAMA 2021, 325 (13) : 1324-26.

Background Reference 02

Reardon. Nature 2021.

Background Reference 03

Delphine. Nature 2021, 596 (7871) : 276-280.

Other Product Names

S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, Delta variant spike RBD

Tested Applications

ELISA, WB, SDS-PAGE

Species

SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein

Physical Properties

Liquid

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