SARS-CoV-2 (COVID-19) Delta Variant Spike RBD (His-Avi Tag) Recombinant Protein
Product Specifications
Background
SARS-CoV-2 delta variant, a variant of concern (VOC), known as B.1.617.2, was detected in India in October of 2020. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 99% of the cases. This variant carries at least 13 mutations in spike protein across the sub lineages, including L452R, D614G, P681R and K417N, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Delta variant was observed globally, which is at least 2.5 times more contagious as the other variants. The Delta variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent.
CAS Number
9000-83-3
NCBI Gene ID
43740578
Swiss Prot
P0DTC1
Accession Number
QHD43416.1
Tag
His-Avi tag at C-terminus
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Infectious Disease, COVID-19
Purity
> 95% as determined by Bis-Tris PAGE
Buffer
PBS (pH 7.4) .
Shipping Conditions
Dry Ice
Storage Conditions
Store in working aliquots at -70˚ C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Calculated Molecular Weight
35 kD
Applications Notes
This recombinant protein can be used for WB and ELISA. For research use only.
NCBI Official Name
Surface glycoprotein
NCBI Organism
Severe acute respiratory syndrome coronavirus 2
Background Reference 01
Zhang et al. JAMA 2021, 325 (13) : 1324-26.
Background Reference 02
Reardon. Nature 2021.
Background Reference 03
Delphine. Nature 2021, 596 (7871) : 276-280.
Other Product Names
S protein RBD, Spike glycoprotein Receptor-binding domain, S glycoprotein RBD, Spike protein RBD, Delta variant spike RBD
Tested Applications
ELISA, WB, SDS-PAGE
Species
SARS-CoV-2 (COVID-19, 2019-nCoV) Spike Protein
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
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