S100A6 Recombinant Protein
Product Specifications
Background
S100 calcium binding protein A6 (S100-A6) is also kown as 2A9, 5B10, CABP, CACY and PRA, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100A6 may function in stimulation of Ca2+ -dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. S100A6 has been shown to interact with S100B and SUGT1.
NCBI Gene ID
6277
Swiss Prot
P06703
Accession Number
AAH01431
Tag
Tag free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle, Other
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-668
Calculated Molecular Weight
10.2 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
S100 calcium binding protein A6
NCBI Organism
Homo sapiens
Background Reference 01
Deloulme, J C, et al., 2000, J. Biol. Chem. (UNITED STATES) 275 (45) : 35302–10.
Background Reference 02
Yang, Q, et al., 1999, Exp. Cell Res. (UNITED STATES) 246 (2) : 501–9.
Background Reference 03
Nowotny, Marcin, et al., 2003, J. Biol. Chem. (United States) 278 (29) : 26923–8.
Other Product Names
S100A6, 2A9, 5B10, CABP, CACY, PRA
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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