Reticulocalbin-3 Recombinant Protein

Reticulocalbin-3 is a member of the CREC family that is involved in the secretory pathway. Members of the CREC family consist of a number of multiple EF-hand domains. Reticulocalbin-3 localizes to the endoplasmic reticulum lumen. The bioinformaticanalysis of Reticulocalbin-3 reveal that it is a putative Ca2+-binding protein. In addition, it has been shown that autoactivation and secretion of PACE4 was increased upon co-expression with Reticulocalbin-3. The proPACE4-RCN-3 complex is plays an important role in the biosynthesis of PACE4.

Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,1mM DTT,10%Glycerol, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.