Repulsive guidance molecule A Recombinant Protein
Product Specifications
Background
Repulsive guidance molecule A (RGMA) is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
CAS Number
9000-83-3
NCBI Gene ID
56963
Swiss Prot
Q96B86
Accession Number
Q96B86
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Neuroscience, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
29.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Repulsive guidance molecule family member a
NCBI Organism
Homo sapiens
Other Product Names
Repulsive guidance molecule A, RGM domain family member A, RGM, RGMA
Species
Human
Physical Properties
Liquid
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