TSLP R Recombinant Protein
Product Specifications
Background
Receptor for thymic stromal lymphopoietin (TSLP) . CRLF2 / TSLPR is a member of the type I cytokine receptor family. Together with the interleukin 7 receptor (IL7R) and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system.
CAS Number
9000-83-3
NCBI Gene ID
64109
Swiss Prot
Q9HC73
Accession Number
NP_071431.2
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
50.4 kDa
Applications Notes
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.4 kDa. The protein migrates as 62-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
Cytokine receptor like factor 2
NCBI Organism
Homo sapiens
Background Reference 01
Lucia Pattarini, et al., 2017, J Exp Med.214 (5) : 1529–1546.
Background Reference 02
Wang J., et al., 2008, Cell. Mol. Immunol. 5:99-106.
Background Reference 03
Soumelis V., et al., 2002, Nat. Immunol. 3:673-680.
Other Product Names
TSLP R, CRLF2, IL-XR, ILXR, p2RY8/CRLF2 fusion, TSLP receptor, TSLPR, CRL2, CRLF2Y, Cytokine receptor-like 2
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
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