TSLP R Recombinant Protein
Product Specifications
Background
Receptor for thymic stromal lymphopoietin (TSLP) . CRLF2 / TSLPR is a member of the type I cytokine receptor family. Together with the interleukin 7 receptor (IL7R) and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system.
NCBI Gene ID
64109
Swiss Prot
Q9HC73
Accession Number
NP_071431.2
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=11-505
Calculated Molecular Weight
50.4 kDa
Applications Notes
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.4 kDa. The protein migrates as 62-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
Cytokine receptor like factor 2
NCBI Organism
Homo sapiens
Background Reference 01
Lucia Pattarini, et al., 2017, J Exp Med.214 (5) : 1529–1546.
Background Reference 02
Wang J., et al., 2008, Cell. Mol. Immunol. 5:99-106.
Background Reference 03
Soumelis V., et al., 2002, Nat. Immunol. 3:673-680.
Other Product Names
TSLP R, CRLF2, IL-XR, ILXR, p2RY8/CRLF2 fusion, TSLP receptor, TSLPR, CRL2, CRLF2Y, Cytokine receptor-like 2
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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