PRL2 Recombinant Protein
Product Specifications
Background
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm, endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
CAS Number
9000-83-3
NCBI Gene ID
8073
Swiss Prot
Q12974
Accession Number
Q12974
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Apoptosis, Cancer, Cell Cycle, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
20.2 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Protein tyrosine phosphatase type IVA, member 2
NCBI Organism
Homo sapiens
Other Product Names
Protein tyrosine phosphatase type IVA 2, PTP4A2, HU-PP-1, OV-1, PTP (CAAXII), Protein-tyrosine phosphatase 4a2, Protein-tyrosine phosphatase of regenerating liver 2, PRL-2
Species
Human
Protein ID
767904139
Physical Properties
Lyophilized
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