PPP1R1A Recombinant Protein
Product Specifications
Background
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B) . Multiple domains in IPP-1 target cellular PP1 complexes.
CAS Number
9000-83-3
NCBI Gene ID
5502
Swiss Prot
Q13522
Accession Number
Q13522
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Homeostasis
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 1mM DTT, 50% Glycerol, pH 8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
19.98 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Protein phosphatase 1 regulatory inhibitor subunit 1A
NCBI Organism
Homo sapiens
Other Product Names
Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1
Species
Human
Protein ID
767904139
Physical Properties
Liquid
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