POMGNT1 Recombinant Protein
Product Specifications
Background
Protein O-Linked-Mannose beta -1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3) .
CAS Number
9000-83-3
NCBI Gene ID
55624
Swiss Prot
Q8WZA1
Accession Number
Q8WZA1
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
69.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
NCBI Organism
Homo sapiens
Other Product Names
Protein O-Linked-Mannose Beta-1, 2-N-Acetylglucosaminyltransferase 1, POMGnT1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1, 2-N-Acetylglucosaminyltransferase I.2, GnT I.2, MGAT1.2
Species
Human
Protein ID
158257574
Physical Properties
Liquid
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