Polypeptide GalNac Transferase 3 Recombinant Protein
Product Specifications
Background
Polypeptide N-acetylgalactosaminyltransferase 3 (GALNT3) belongs to the glycosyltransferase 2 family and galNAc-T subfamily. It expressed in organs that contain secretory epithelial glands and it highly expressed in pancreas, skin, kidney and testis. There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding .This protein plays a major role in regulating phosphate levels within the body (phosphate homeostasis) . Among its many functions, phosphate plays a critical role in the formation and growth of bones in childhood and helps maintain bone strength in adults.
CAS Number
9000-83-3
NCBI Gene ID
2591
Swiss Prot
Q14435
Accession Number
Q14435
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-355
Calculated Molecular Weight
69.1 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Polypeptide N-acetylgalactosaminyltransferase 3
NCBI Organism
Homo sapiens
Other Product Names
Polypeptide N-acetylgalactosaminyltransferase 3, Polypeptide GalNAc transferase 3, GalNAc-T3, pp-GaNTase 3, Protein-UDP acetylgalactosaminyltransferase 3, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3, HFTC, HHS, GALNT3
Species
Human
Physical Properties
Liquid
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