Peroxiredoxin-4 Recombinant Protein
Product Specifications
Background
Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
NCBI Gene ID
10549
Swiss Prot
Q13162
Accession Number
Q13162
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Cell Cycle, Signal Transduction, Other
Buffer
Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM DTT, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-036
Calculated Molecular Weight
33.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Peroxiredoxin 4
NCBI Organism
Homo sapiens
Other Product Names
Peroxiredoxin-4, Antioxidant Enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin Peroxidase AO372, Thioredoxin-Dependent Peroxide Reductase A0372, PRDX4
Species
Human
Protein ID
767904139
Physical Properties
Liquid
CAS Number
9000-83-3
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